Positive and Negative Regulation of the Cardiovascular Transcription Factor KLF5 by p300 and the Oncogenic Regulator SET through Interaction and Acetylation on the DNA-Binding Domain

Here we show a novel pathway of transcriptional regulation of a DNA-binding transcription factor by coupled interaction and modification (e.g., acetylation) through the DNA-binding domain (DBD). The oncogenic regulator SET was isolated by affinity purification of factors interacting with the DBD of...

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Detalhes bibliográficos
Main Authors: Miyamoto, Saku, Suzuki, Toru, Muto, Shinsuke, Aizawa, Kenichi, Kimura, Akatsuki, Mizuno, Yoshiko, Nagino, Tomoko, Imai, Yasushi, Adachi, Naruhiko, Horikoshi, Masami, Nagai, Ryozo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC262669/
https://ncbi.nlm.nih.gov/pubmed/14612398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.23.8528-8541.2003
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