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Molecular dynamics calculations suggest a conduction mechanism for the M2 proton channel from influenza A virus
The M2 protein of the influenza A virus is activated by low endosomal pH and performs the essential function of proton transfer into the viral interior. The resulting decrease in pH within the virion is essential for the uncoating and further replication of the viral genetic material. The x-ray crys...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2626606/ https://ncbi.nlm.nih.gov/pubmed/19144924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811720106 |
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