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Mechanisms and Molecular Probes of Sirtuins

Sirtuins are critical regulators of many cellular processes including insulin secretion, the cell cycle, and apoptosis. Sirtuins are associated with a variety of age-associated diseases such as type II diabetes, obesity, and Alzheimer’s disease. A thorough understanding of sirtuin chemical mechanism...

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Détails bibliographiques
Auteurs principaux: Smith, Brian C., Hallows, William C., Denu, John M.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626554/
https://ncbi.nlm.nih.gov/pubmed/18940661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2008.09.009
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