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Transgenic Induction of Vascular Endothelial Growth Factor-C Is Strongly Angiogenic in Mouse Embryos but Leads to Persistent Lymphatic Hyperplasia in Adult Tissues

Vascular endothelial growth factor-C (VEGF-C) is the quintessential lymphangiogenic growth factor that is required for the development of the lymphatic system and is capable of stimulating lymphangiogenesis in adults by activating its receptor, VEGFR-3. Although VEGF-C is a major candidate molecule...

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Detalhes bibliográficos
Main Authors: Lohela, Marja, Heloterä, Hanna, Haiko, Paula, Dumont, Daniel J., Alitalo, Kari
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626399/
https://ncbi.nlm.nih.gov/pubmed/18988807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080378
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