Proteomic-Based Detection of a Protein Cluster Dysregulated during Cardiovascular Development Identifies Biomarkers of Congenital Heart Defects

BACKGROUND: Cardiovascular development is vital for embryonic survival and growth. Early gestation embryo loss or malformation has been linked to yolk sac vasculopathy and congenital heart defects (CHDs). However, the molecular pathways that underlie these structural defects in humans remain largely...

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Detalhes bibliográficos
Main Authors: Nath, Anjali K., Krauthammer, Michael, Li, Puyao, Davidov, Eugene, Butler, Lucas C., Copel, Joshua, Katajamaa, Mikko, Oresic, Matej, Buhimschi, Irina, Buhimschi, Catalin, Snyder, Michael, Madri, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626248/
https://ncbi.nlm.nih.gov/pubmed/19156209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004221
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