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TLR agonists abrogate costimulation blockade-induced mixed chimerism and transplantation tolerance
We investigated the mechanisms by which toll-like receptor (TLR) agonists affect the induction of mixed chimerism and skin allograft survival in mice treated with costimulation blockade (CB). We report that TLR agonists prevent the generation of mixed chimerism by breaking tolerance in the alloreact...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2626129/ https://ncbi.nlm.nih.gov/pubmed/19120285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1196/annals.1447.034 |
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