Cargando...

TLR agonists abrogate costimulation blockade-induced mixed chimerism and transplantation tolerance

We investigated the mechanisms by which toll-like receptor (TLR) agonists affect the induction of mixed chimerism and skin allograft survival in mice treated with costimulation blockade (CB). We report that TLR agonists prevent the generation of mixed chimerism by breaking tolerance in the alloreact...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Miller, David M., Thornley, Thomas, Pearson, Todd, Yamazaki, Masahiro, Brehm, Michael A., Rossini, Aldo A., Greiner, Dale L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626129/
https://ncbi.nlm.nih.gov/pubmed/19120285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1196/annals.1447.034
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!