Adjuvant 5-fluorouracil and folinic acid vs observation for pancreatic cancer: composite data from the ESPAC-1 and -3(v1) trials

The ESPAC-1, ESPAC-1 plus, and early ESPAC-3(v1) results (458 randomized patients; 364 deaths) were used to estimate the effectiveness of adjuvant 5FU/FA vs resection alone for pancreatic cancer using meta-analysis. The pooled hazard ratio of 0.70 (95% CI=0.55–0.88) P=0.003, and the median survival...

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Bibliographische Detailangaben
Hauptverfasser: Neoptolemos, J P, Stocken, D D, Tudur Smith, C, Bassi, C, Ghaneh, P, Owen, E, Moore, M, Padbury, R, Doi, R, Smith, D, Büchler, M W
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
Schlagworte:
Clinical Study
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2625958/
https://ncbi.nlm.nih.gov/pubmed/19127260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604838
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