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The Differential Requirement for Cyclin-Dependent Kinase Activities Distinguishes Two Functions of Herpes Simplex Virus Type 1 ICP0

Herpes simplex virus type 1 (HSV-1) ICP0 directs the degradation of cellular proteins associated with nuclear structures called ND10, a function thought to be closely associated with its broad transactivating activity. Roscovitine (Rosco), an inhibitor of cyclin-dependent kinases (cdks), inhibits th...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Davido, David J., von Zagorski, William F., Maul, Gerd G., Schaffer, Priscilla A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262587/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14610183/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.23.12603-12616.2003
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