Covalently Linked Human Immunodeficiency Virus Type 1 gp120/gp41 Is Stably Anchored in Rhabdovirus Particles and Exposes Critical Neutralizing Epitopes

Rabies virus (RV) vaccine strain-based vectors show significant promise as potential live-attenuated vaccines against human immunodeficiency virus type 1 (HIV-1). Here we describe a new RV construct that will also likely have applications as a live-attenuated or killed-particle immunogen. We have cr...

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Bibliographische Detailangaben
Hauptverfasser: McKenna, Philip M., Pomerantz, Roger J., Dietzschold, Bernhard, McGettigan, James P., Schnell, Matthias J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC262580/
https://ncbi.nlm.nih.gov/pubmed/14610200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.23.12782-12794.2003
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