Replication Checkpoint Protein Mrc1 Is Regulated by Rad3 and Tel1 in Fission Yeast

Fission yeast Mrc1 (mediator of replication checkpoint 1) is an adaptor checkpoint protein required for Rad3-dependent activation of the checkpoint kinase Cds1 in response to arrest of replication forks. Here we report studies on the regulation of Mrc1 by phosphorylation. Replication arrest induced...

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Detalhes bibliográficos
Main Authors: Zhao, Hui, Tanaka, Katsunori, Nogochi, Eishi, Nogochi, Chiaki, Russell, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC262408/
https://ncbi.nlm.nih.gov/pubmed/14585996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.22.8395-8403.2003
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