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Pseudomonas aeruginosa immunotype 5 polysaccharide-toxin A conjugate vaccine.

Polysaccharide (PS) derived from Pseudomonas aeruginosa immunotype 5 lipopolysaccharide was covalently coupled to toxin A by reductive amination with adipic acid dihydrazide as a spacer molecule. The resulting PS-toxin A conjugate was composed of 27.5% PS and 72.5% toxin A. The conjugate was compose...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Cryz, S J, Furer, E, Sadoff, J C, Germanier, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1986
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262213/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3082756/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.52.1.161-165.1986
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