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Brucella fractions behave as nonspecific mitogens and polyclonal B-cell activators for human lymphocytes.

Two lipid-A-free fractions which were extracted from Brucella melitensis and were designated PI and SF stimulated human unsensitized mononuclear cells to proliferate and to secrete immunoglobulins. Both of these effects were observed in cultures of peripheral blood, tonsils, and cord blood lymphocyt...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Vendrell, J P, Rabesandratana, H, Huguet, M F, Cannat, A, Serre, A
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1985
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262173/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3876286/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.50.1.310-316.1985
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