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In vitro and in vivo differentiation into B cells, T cells, and myeloid cells of primitive yolk sac hematopoietic precursor cells expanded >100-fold by coculture with a clonal yolk sac endothelial cell line

The yolk sac, first site of hematopoiesis during mammalian development, contains not only hematopoietic stem cells but also the earliest precursors of endothelial cells. We have previously shown that a nonadherent yolk sac cell population (WGA(+), density <1.077, AA4.1(+)) can give rise to B cell...

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Detalhes bibliográficos
Principais autores: Lu, Li-Sheng, Wang, Shur-Jen, Auerbach, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26213/
https://ncbi.nlm.nih.gov/pubmed/8962132
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