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Pds1p Is Required for Meiotic Recombination and Prophase I Progression in Saccharomyces cerevisiae

Sister-chromatid separation at the metaphase–anaphase transition is regulated by a proteolytic cascade. Destruction of the securin Pds1p liberates the Esp1p separase, which ultimately targets the mitotic cohesin Mcd1p/Scc1p for destruction. Pds1p stabilization by the spindle or DNA damage checkpoint...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cooper, Katrina F., Mallory, Michael J., Guacci, Vincent, Lowe, Katherine, Strich, Randy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621190/
https://ncbi.nlm.nih.gov/pubmed/19001291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.095513
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