Nuclear Factor-κB Binds to the Epstein-Barr Virus LMP1 Promoter and Upregulates Its Expression

The latent membrane protein 1 (LMP1) oncogene carried by Epstein-Barr virus (EBV) is essential for transformation and maintenance of EBV-immortalized B cells in vitro, and it is expressed in most EBV-associated tumor types. The activation of the NF-κB pathway by LMP1 plays a critical role in the upr...

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Detalhes bibliográficos
Main Authors: Johansson, Pegah, Jansson, Ann, Rüetschi, Ulla, Rymo, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2620919/
https://ncbi.nlm.nih.gov/pubmed/19019967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01637-08
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