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MAVS Dimer Is a Crucial Signaling Component of Innate Immunity and the Target of Hepatitis C Virus NS3/4A Protease

The mitochondrial antiviral signaling (MAVS) protein plays a central role in innate antiviral immunity. Upon recognition of a virus, intracellular receptors of the RIG-I-like helicase family interact with MAVS to trigger a signaling cascade. In this study, we investigate the requirement of the MAVS...

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Autori principali: Baril, Martin, Racine, Marie-Eve, Penin, François, Lamarre, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2620913/
https://ncbi.nlm.nih.gov/pubmed/19036819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01659-08
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