Null Mutations in a Nudix Gene, ygdP, Implicate an Alarmone Response in a Novel Suppression of Hybrid Jamming

Induction of the toxic LamB-LacZ protein fusion, Hyb42-1, leads to a lethal generalized protein export defect. The prlF1 suppressor causes hyperactivation of the cytoplasmic Lon protease and relieves the inducer sensitivity of Hyb42-1. Since prlF1 does not cause a detectable change in the stability...

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Pubblicato in:	J Bacteriol
Autori principali:	Hand, Nicholas J., Silhavy, Thomas J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Genetics and Molecular Biology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262091/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14594825/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.22.6530-6539.2003
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