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Repair of the U(L)21 Locus in Pseudorabies Virus Bartha Enhances the Kinetics of Retrograde, Transneuronal Infection In Vitro and In Vivo

The attenuated pseudorabies virus (PRV) strain Bartha contains several characterized mutations that affect its virulence and ability to spread through neural circuits. This strain contains a small genomic deletion that abrogates anterograde spread and is widely used as a retrograde-restricted neural...

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Main Authors: Curanović, D., Lyman, M. G., Bou-Abboud, C., Card, J. P., Enquist, L. W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2620901/
https://ncbi.nlm.nih.gov/pubmed/19019952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02102-08
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