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Repair of the U(L)21 Locus in Pseudorabies Virus Bartha Enhances the Kinetics of Retrograde, Transneuronal Infection In Vitro and In Vivo

The attenuated pseudorabies virus (PRV) strain Bartha contains several characterized mutations that affect its virulence and ability to spread through neural circuits. This strain contains a small genomic deletion that abrogates anterograde spread and is widely used as a retrograde-restricted neural...

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Bibliografiske detaljer
Main Authors: Curanović, D., Lyman, M. G., Bou-Abboud, C., Card, J. P., Enquist, L. W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2620901/
https://ncbi.nlm.nih.gov/pubmed/19019952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02102-08
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