Human trophoblast and choriocarcinoma expression of the growth factor pleiotrophin attributable to germ-line insertion of an endogenous retrovirus

Retroviral elements are found in abundance throughout the human genome but only rarely have alterations of endogenous genes by retroviral insertions been described. Herein we report that a human endogenous retrovirus (HERV) type C is inserted in the human growth factor gene pleiotrophin (PTN) betwee...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Schulte, Anke M., Lai, Shoupeng, Kurtz, Andreas, Czubayko, Frank, Riegel, Anna T., Wellstein, Anton
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1996
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26209/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8962128/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.25.14759
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