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Dynamic Association of the Replication Initiator and Transcription Factor DnaA with the Bacillus subtilis Chromosome during Replication Stress

DnaA functions as both a transcription factor and the replication initiator in bacteria. We characterized the DNA binding dynamics of DnaA on a genomic level. Based on cross-linking and chromatin immunoprecipitation data, DnaA binds at least 17 loci, 15 of which are regulated transcriptionally in re...

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Detalhes bibliográficos
Main Authors: Breier, Adam M., Grossman, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2620820/
https://ncbi.nlm.nih.gov/pubmed/19011033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01294-08
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