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Melanoma angiogenesis and metastasis modulated by ribozyme targeting of the secreted growth factor pleiotrophin

Clinical and experimental evidence suggests that spreading of malignant cells from a localized tumor (metastasis) is directly related to the number of microvessels in the primary tumor. This tumor angiogenesis is thought to be mediated by tumor-cell-derived growth factors. However, most tumor cells...

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Autors principals: Czubayko, Frank, Schulte, Anke M., Berchem, Guy J., Wellstein, Anton
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC26208/
https://ncbi.nlm.nih.gov/pubmed/8962127
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