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Melanoma angiogenesis and metastasis modulated by ribozyme targeting of the secreted growth factor pleiotrophin

Clinical and experimental evidence suggests that spreading of malignant cells from a localized tumor (metastasis) is directly related to the number of microvessels in the primary tumor. This tumor angiogenesis is thought to be mediated by tumor-cell-derived growth factors. However, most tumor cells...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Czubayko, Frank, Schulte, Anke M., Berchem, Guy J., Wellstein, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26208/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8962127/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.25.14753
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