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Acetohydroxyacid Synthase, a Novel Target for Improvement of l-Lysine Production by Corynebacterium glutamicum

The influence of acetohydroxy acid synthase (AHAS) on l-lysine production by Corynebacterium glutamicum was investigated. An AHAS with a deleted C-terminal domain in the regulatory subunit IlvN was engineered by truncating the ilvN gene. Compared to the wild-type AHAS, the newly constructed enzyme s...

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Bibliographic Details
Main Authors: Blombach, Bastian, Hans, Stephan, Bathe, Brigitte, Eikmanns, Bernhard J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2620725/
https://ncbi.nlm.nih.gov/pubmed/19047397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01844-08
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