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Construction and Characterization of an Attenuated Listeria monocytogenes Strain for Clinical Use in Cancer Immunotherapy

Listeria monocytogenes has been exploited previously as a vaccine vector for the delivery of heterologous proteins such as tumor-specific antigens for active cancer immunotherapy. However, for effective use of live vector in clinics, safety is a major concern. In the present study, we describe an ir...

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Main Authors: Wallecha, Anu, Maciag, Paulo Cesar, Rivera, Sandra, Paterson, Yvonne, Shahabi, Vafa
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2620657/
https://ncbi.nlm.nih.gov/pubmed/19020110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00274-08
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