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Antibodies to O-antigen of lipopolysaccharide are protective against neonatal infection with Escherichia coli K1.

Monoclonal IgM specific for the O18 antigen conferred passive protection to 1-week-old rats against bacteremia and killing after oral challenge with O18:K1 Escherichia coli. Specific protection of the pups was also achieved by immunizing the pregnant rats with purified O18 lipopolysaccharide. We sup...

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Main Authors: Pluschke, G, Achtman, M
格式: Artigo
語言:Inglês
出版: 1985
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC262024/
https://ncbi.nlm.nih.gov/pubmed/2410365
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