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Efficient Calculation of Configurational Entropy from Molecular Simulations by Combining the Mutual-Information Expansion and Nearest-Neighbor Methods

Changes in the configurational entropies of molecules make important contributions to free energies of reaction for processes such as protein-folding, noncovalent association, and conformational change. However, obtaining entropy from molecular simulations represents a long-standing computational ch...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hnizdo, Vladimir, Tan, Jun, Killian, Benjamin J., Gilson, Michael K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2620139/
https://ncbi.nlm.nih.gov/pubmed/18293293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.20919
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