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Kinesin-5 is essential for growth cone turning

Inhibition of kinesin-5, a mitotic motor also expressed in neurons [1], causes axons to grow faster due to alterations in the forces on the microtubules (MTs) in the axonal shaft [2-4]. Here, we investigated whether kinesin-5 plays a role in growth cone guidance. Growth cone turning requires that MT...

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Bibliografiska uppgifter
Huvudupphovsmän: Nadar, Vidya C., Ketschek, Andrea, Myers, Kenneth A., Gallo, Gianluca, Baas, Peter W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2617768/
https://ncbi.nlm.nih.gov/pubmed/19084405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.11.021
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