IGFBP3 Colocalizes with and Regulates Hypocretin (Orexin)

BACKGROUND: The sleep disorder narcolepsy is caused by a vast reduction in neurons producing the hypocretin (orexin) neuropeptides. Based on the tight association with HLA, narcolepsy is believed to result from an autoimmune attack, but the cause of hypocretin cell loss is still unknown. We performe...

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Detalhes bibliográficos
Main Authors: Honda, Makoto, Eriksson, Krister S., Zhang, Shengwen, Tanaka, Susumu, Lin, Ling, Salehi, Ahmad, Hesla, Per Egil, Maehlen, Jan, Gaus, Stephanie E., Yanagisawa, Masashi, Sakurai, Takeshi, Taheri, Shahrad, Tsuchiya, Kuniaki, Honda, Yutaka, Mignot, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2617764/
https://ncbi.nlm.nih.gov/pubmed/19158946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004254
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