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Please do not disturb: Destruction of chromatin structure by supravital nucleic acid probes revealed by a novel assay of DNA-histone interaction

The biomarkers designed to be used supravitally are expected to have minimal effect on structure and function of the cell. Unfortunately nearly all fluorochromes developed to probe live cells interact in undesired way with cellular constituents and affect functional pathways. Herein we comment on po...

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Detalhes bibliográficos
Main Authors: Wlodkowic, Donald, Darzynkiewicz, Zbigniew
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2617724/
https://ncbi.nlm.nih.gov/pubmed/18671237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.20622
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