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Imatinib Suppresses Cryoglobulinemia and Secondary Membranoproliferative Glomerulonephritis
Imatinib is a receptor tyrosine kinase inhibitor that blocks the activity of c-Abl, c-Kit, and PDGF receptors. We tested the protective effects of imatinib in thymic stromal lymphopoietin transgenic mice, a model of cryoglobulinemia and associated membranoproliferative glomerulonephritis (MPGN), in...
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| Main Authors: | , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Nephrology
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615727/ https://ncbi.nlm.nih.gov/pubmed/19020005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008010036 |
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