The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3′ mRNA processing factors

The CDC73 tumor suppressor gene is mutationally inactivated in hereditary and sporadic parathyroid tumors. Its product, the Cdc73 protein, is a component of the RNA polymerase II and chromatin-associated human Paf1 complex (Paf1C). Here, we show that Cdc73 physically associates with the cleavage and...

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Detalhes bibliográficos
Main Authors: Rozenblatt-Rosen, Orit, Nagaike, Takashi, Francis, Joshua M., Kaneko, Syuzo, Glatt, Karen A., Hughes, Christina M., LaFramboise, Thomas, Manley, James L., Meyerson, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615665/
https://ncbi.nlm.nih.gov/pubmed/19136632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812023106
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