The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3′ mRNA processing factors

The CDC73 tumor suppressor gene is mutationally inactivated in hereditary and sporadic parathyroid tumors. Its product, the Cdc73 protein, is a component of the RNA polymerase II and chromatin-associated human Paf1 complex (Paf1C). Here, we show that Cdc73 physically associates with the cleavage and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rozenblatt-Rosen, Orit, Nagaike, Takashi, Francis, Joshua M., Kaneko, Syuzo, Glatt, Karen A., Hughes, Christina M., LaFramboise, Thomas, Manley, James L., Meyerson, Matthew
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2009
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615665/
https://ncbi.nlm.nih.gov/pubmed/19136632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812023106
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