Rex1p deficiency leads to accumulation of precursor initiator tRNA(Met) and polyadenylation of substrate RNAs in Saccharomyces cerevisiae

A synthetic genetic array was used to identify lethal and slow-growth phenotypes produced when a mutation in TRM6, which encodes a tRNA modification enzyme subunit, was combined with the deletion of any non-essential gene in Saccharomyces cerevisiae. We found that deletion of the REX1 gene resulted...

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Bibliografiska uppgifter
Huvudupphovsmän: Ozanick, Sarah G., Wang, Xuying, Costanzo, Michael, Brost, Renee L., Boone, Charles, Anderson, James T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2009
Ämnen:
Molecular Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615624/
https://ncbi.nlm.nih.gov/pubmed/19042972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn925
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