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Twist-1 regulates the miR-199a/214 cluster during development

MicroRNAs are known to regulate developmental processes but their mechanism of regulation remains largely uncharacterized. We show the transcription factor Twist-1 drives the expression of a 7.9-kb noncoding RNA transcript (from the Dynamin-3 gene intron) that encodes a miR-199a and miR-214 cluster....

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Detalhes bibliográficos
Main Authors: Lee, Youn-Bok, Bantounas, Ioannis, Lee, Do-Young, Phylactou, Leonidas, Caldwell, Maeve A., Uney, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615617/
https://ncbi.nlm.nih.gov/pubmed/19029138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn920
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