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MicroRNAs 373 and 520c Are Downregulated in Prostate Cancer, Suppress CD44 Translation and Enhance Invasion of Prostate Cancer Cells in vitro

Prostate cancer (PCa), like most human cancers, features dysregulated CD44 expression. It loses expression of CD44 standard (CD44s), present in benign epithelium, and overexpresses a less abundant splice isoform, CD44v7-10. MicroRNAs 373 and 520c putatively regulate CD44. The levels of these two mic...

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Detalhes bibliográficos
Main Authors: Yang, Kui, Handorean, Alina M., Iczkowski, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615593/
https://ncbi.nlm.nih.gov/pubmed/19158933
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