Growth Inhibition and Regression of Lung Tumors by Silibinin: Modulation of Angiogenesis by Macrophage-associated Cytokines, and NF-κB and STAT3

The latency period for lung tumor progression offers a window of opportunity for therapeutic intervention. Herein, we studied the effect of oral silibinin (742 mg/kg body wt, 5 days/wk for 10 wks) on the growth and progression of established lung adenocarcinomas in A/J mice. Silibinin strongly decre...

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Main Authors: Tyagi, Alpna, Singh, Rana P., Ramasamy, Kumaraguruparan, Raina, Komal, Rodente, Elizabeth F., Dwyer-Nield, Lori D., Radcliffe, Richard A., Malkinson, Alvin M., Agarwal, Rajesh
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615181/
https://ncbi.nlm.nih.gov/pubmed/19139021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-08-0095
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