Toll-Like Receptor Adaptor MyD88 is Essential for Pathogen Control During Oral Toxoplasma gondii Infection but not Adaptive Immunity Induced by a Vaccine Strain of the Parasite

Toll-like receptor (TLR)/MyD88 activation is important in host resistance to Toxoplasma gondii during i. p. infection, but the function of this signaling pathway during oral infection, in which mucosal immunity assumes a predominant role, has not been examined. Here, we show that MyD88(−/−) mice fai...

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Main Authors: Sukhumavasi, Woraporn, Egan, Charlotte E., Warren, Amy L., Taylor, Gregory A., Fox, Barbara A., Bzik, David J., Denkers, Eric Y.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614926/
https://ncbi.nlm.nih.gov/pubmed/18714019
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