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Activation of the Maternal Immune System Alters Cerebellar Development in the Offspring

A common pathological finding in autism is a localized deficit in Purkinje cells (PCs). Cerebellar abnormalities have also been reported in schizophrenia. Using a mouse model that exploits a known risk factor for these disorders, maternal infection, we asked if the offspring of pregnant mice given a...

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Detalhes bibliográficos
Main Authors: Shi, Limin, Smith, Stephen E. P., Malkova, Natalia, Tse, Doris, Su, Yixuan, Patterson, Paul H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614890/
https://ncbi.nlm.nih.gov/pubmed/18755264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2008.07.012
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