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Extracellular proteolysis by matrix metalloproteinase-9 drives dendritic spine enlargement and long-term potentiation coordinately

Persistent dendritic spine enlargement is associated with stable long-term potentiation (LTP), and the latter is thought to underlie long-lasting memories. Extracellular proteolytic remodeling of the synaptic microenvironment could be important for such plasticity, but whether or how proteolytic rem...

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Autores principales: Wang, Xiao-bin, Bozdagi, Ozlem, Nikitczuk, Jessica S., Zhai, Zu Wei, Zhou, Qiang, Huntley, George W.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614793/
https://ncbi.nlm.nih.gov/pubmed/19047646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807248105
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