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A genome-wide admixture scan identifies MYH9 as a candidate locus associated with non-diabetic end stage renal disease in African Americans

End stage renal disease (ESRD) has a four times higher incidence in African Americans compared to European Americans. This led to the hypothesis that susceptibility alleles for ESRD have a higher frequency in West African than European gene pool. We performed a genome-wide admixture scan in 1,372 ES...

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Autores principales: Linda Kao, WH, Klag, Michael J, Meoni, Lucy A, Reich, David, Berthier-Schaad, Yvette, Li, Man, Coresh, Josef, Patterson, Nick, Tandon, Arti, Powe, Neil R, Fink, Nancy E, Sadler, John H, Weir, Matthew R, Abboud, Hanna E, Adler, Sharon, Divers, Jasmin, Iyengar, Sudha K, Freedman, Barry I, Kimmel, Paul L, Knowler, William C, Kohn, Orly F, Kramp, Kristopher, Leehey, David J, Nicholas, Susanne, Pahl, Madeleine, Schelling, Jeffrey R, Sedor, John R, Thornley-Brown, Denyse, Winkler, Cheryl A, Smith, Michael W., Parekh, Rulan S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614692/
https://ncbi.nlm.nih.gov/pubmed/18794854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.232
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