Ranolazine Shortens Repolarization in Patients with Sustained Inward Sodium Current Due To Type-3 Long QT Syndrome

INTRODUCTION: One form of the hereditary long QT-syndrome, LQT3-ΔKPQ, is associated with sustained inward sodium current during membrane depolarization. Ranolazine reduces late sodium channel current, and we hypothesized that ranolazine would have beneficial effects on electrical and mechanical card...

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Xehetasun bibliografikoak
Egile Nagusiak: Moss, Arthur J., Zareba, Wojciech, Schwarz, Karl Q., Rosero, Spencer, McNitt, Scott, Robinson, Jennifer L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614458/
https://ncbi.nlm.nih.gov/pubmed/18662191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1540-8167.2008.01246.x
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