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Regulation of the Nanog Gene by Both Positive and Negative cis-Regulatory Elements in Embryonal Carcinoma Cells and Embryonic Stem Cells

The transcription factor Nanog is essential for mammalian embryogenesis, as well as the pluripotency of embryonic stem (ES) cells. Work with ES cells and embryonal carcinoma (EC) cells previously identified positive and negative cis-regulatory elements that influence the activity of the Nanog promot...

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Detalhes bibliográficos
Main Authors: Boer, Brian, Cox, Jesse L., Claassen, David, Mallanna, Sunil Kumar, Desler, Michelle, Rizzino, Angie
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614456/
https://ncbi.nlm.nih.gov/pubmed/18537119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrd.20943
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