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Regulation of the Nanog Gene by Both Positive and Negative cis-Regulatory Elements in Embryonal Carcinoma Cells and Embryonic Stem Cells

The transcription factor Nanog is essential for mammalian embryogenesis, as well as the pluripotency of embryonic stem (ES) cells. Work with ES cells and embryonal carcinoma (EC) cells previously identified positive and negative cis-regulatory elements that influence the activity of the Nanog promot...

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Bibliographische Detailangaben
Hauptverfasser: Boer, Brian, Cox, Jesse L., Claassen, David, Mallanna, Sunil Kumar, Desler, Michelle, Rizzino, Angie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614456/
https://ncbi.nlm.nih.gov/pubmed/18537119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrd.20943
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