Isopentenyl pyrophosphate activated CD56(+) γδ T lymphocytes display potent anti-tumor activity towards human squamous cell carcinoma

PURPOSE: The expression of CD56, a natural killer (NK) cell-associated molecule, on αβ T lymphocytes correlates with their increased anti-tumor effector function. CD56 is also expressed on a subset of γδ T cells. However, anti-tumor effector functions of CD56+ γδ T cells are poorly characterized. EX...

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Bibliographic Details
Main Authors: Alexander, Alan A.Z., Maniar, Amudhan, Cummings, Jean-Saville, Hebbeler, Andrew M., Schulze, Dan H., Gastman, Brian R., Pauza, C. David, Strome, Scott E., Chapoval, Andrei I.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614380/
https://ncbi.nlm.nih.gov/pubmed/18594005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4912
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