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Increasing Hippocampal Acetylcholine Levels Enhances Behavioral Performance in an Animal Model of Diencephalic Amnesia
Pyrithiamine-induced thiamine deficiency (PTD) was used to produce a rodent model of Wernicke-Korsakoff syndrome that results in acute neurological disturbances, thalamic lesions, and learning and memory impairments. There is also cholinergic septo-hippocampal dysfunction in the PTD model. Systemic...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614338/ https://ncbi.nlm.nih.gov/pubmed/18706897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.07.090 |
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