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Increasing Hippocampal Acetylcholine Levels Enhances Behavioral Performance in an Animal Model of Diencephalic Amnesia

Pyrithiamine-induced thiamine deficiency (PTD) was used to produce a rodent model of Wernicke-Korsakoff syndrome that results in acute neurological disturbances, thalamic lesions, and learning and memory impairments. There is also cholinergic septo-hippocampal dysfunction in the PTD model. Systemic...

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Autori principali: Roland, Jessica J., Mark, Katherine, Vetreno, Ryan P., Savage, Lisa M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614338/
https://ncbi.nlm.nih.gov/pubmed/18706897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.07.090
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