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CARGO-SORTING SIGNALS PROMOTE POLYMERIZATION OF ADAPTOR PROTEIN-1 IN AN ARF1•GTP-INDEPENDENT MANNER
Adaptor protein-1 (AP-1) is recruited onto the trans-Golgi network via binding to Arf-1•GTP, cargo-sorting signals and phosphoinositides, where it orchestrates the assembly of clathrin-coated vesicular carriers that transport cargo molecules to endosomes. Here we show that cytosolic AP-1 polymerizes...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614314/ https://ncbi.nlm.nih.gov/pubmed/18762162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.08.009 |
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