Integrin α(IIb)β(3) in a Membrane Environment Remains the Same Height after Mn(2+) Activation when Observed by Cryo-electron Tomography

Integrins perform the critical function of signalling cell attachment to the extracellular matrix or to other cells. This signalling is done through a structural change propagated bidirectionally across the plasma membrane. Integrin activation has been extensively studied with ectodomain constructs,...

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Bibliographic Details
Main Authors:	Ye, Feng, Liu, Jun, Winkler, Hanspeter, Taylor, Kenneth A.
Format:	Artigo
Language:	Inglês
Published:	2008
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2614134/ https://ncbi.nlm.nih.gov/pubmed/18405917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.03.014
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Integrin α(IIb)β(3) in a Membrane Environment Remains the Same Height after Mn(2+) Activation when Observed by Cryo-electron Tomography

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