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Tibolone Rapidly Attenuates the GABA(B) Response in Hypothalamic Neurones
Tibolone is primarily used for the treatment of climacteric symptoms. Tibolone is rapidly converted into three major metabolites: 3α- and 3β-hydroxy-tibolone (3α- and 3βOH-tibolone), which have oestrogenic effects, and the Δ4-isomer (Δ4-tibolone), which has progestogenic and androgenic effects. Sinc...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613946/ https://ncbi.nlm.nih.gov/pubmed/19094079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2826.2008.01789.x |
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