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Inhibition of hepatocelluar carcinoma MAT2A and MAT2beta gene expressions by single and dual small interfering RNA

RNA interference (RNAi) has been successfully applied in suppression of hepatic cancer genes. In hepatocelluar carcinoma cell, one methionine adenosyltransferase (MAT) isozyme, MATII was found to have two catalytic subunits which were encoded by MAT2A and MAT2β respectively. During tumorigeness of h...

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Bibliographic Details
Main Authors: Wang, Qun, Liu, Quan-yan, Liu, Zhi-Su, Qian, Qun, Sun, Quan, Pan, Ding-yu
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613873/
https://ncbi.nlm.nih.gov/pubmed/19025580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-27-72
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