GLUCOCORTICOIDS INDUCE TRANSACTIVATION OF TIGHT JUNCTION GENES OCCLUDIN AND CLAUDIN-5 IN RETINAL ENDOTHELIAL CELLS VIA A NOVEL CIS-ELEMENT

Tight junctions between vascular endothelial cells help to create the blood-brain and blood-retinal barriers. Breakdown of the retinal tight junction complex is problematic in several disease states including diabetic retinopathy. Glucocorticoids can restore and/or preserve the endothelial barrier t...

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Bibliographic Details
Main Authors: Felinski, Edward A., Cox, Amy E., Phillips, Brett E., Antonetti, David A.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613867/
https://ncbi.nlm.nih.gov/pubmed/18501346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2008.01.002
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