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Synthesis, Modeling, and Biological Evaluation of Analogues of the Semisynthetic Brevetoxin Antagonist β-Naphthoyl-Brevetoxin

Brevetoxins are neurotoxic compounds produced by the dinoflagellate Karenia brevis. Extensive blooms induce neurotoxic shellfish poisoning (NSP) and asthma-like symptoms in humans. β-naphthoyl-brevetoxin, the first semisynthetic brevetoxin antagonist, has been defined as the lead compound in the inv...

詳細記述

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書誌詳細
主要な著者: Michelliza, Sophie, Abraham, William M., Jacocks, Henry M., Schuster, Thomas, Baden, Daniel G.
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613567/
https://ncbi.nlm.nih.gov/pubmed/18000915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200700317
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