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Uncoupling of Myocardial β-Adrenergic Receptor Signaling During Coronary Artery Bypass Grafting: The Role of GRK2
BACKGROUND: Cardiopulmonary bypass (CPB) and cardioplegic arrest during cardiac surgery leads to desensitization of myocardial β-adrenergic receptors (β-ARs). Impaired signaling through this pathway can have a detrimental effect on ventricular function and increased need for inotropic support. The m...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613564/ https://ncbi.nlm.nih.gov/pubmed/18805158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2008.05.042 |
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