Melatonin attenuates calpain upregulation, axonal damage and neuronal death in spinal cord injury in rats

Multiple investigations in vivo have shown that melatonin (MEL) has a neuroprotective effect in the treatment of spinal cord injury (SCI). This study investigates the role of MEL as an intervening agent for ameliorating Ca(2+)-mediated events, including activation of calpain, following its administr...

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Autors principals: Samantaray, Supriti, Sribnick, Eric A., Das, Arabinda, Knaryan, Varduhi H., Matzelle, D. Denise, Yallapragada, Anil V., Reiter, Russel J., Ray, Swapan K., Banik, Naren L.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613550/
https://ncbi.nlm.nih.gov/pubmed/18086148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-079X.2007.00534.x
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